Anti-Histone H1.X/FITC Conjugated抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-Histone H1.X/FITC Conjugated抗体

Anti-Histone H1.X/FITC Conjugated抗体

商家询价

产品名称: Anti-Histone H1.X/FITC Conjugated抗体

英文名称: Anti-Histone H1.X/FITC

产品编号: YB--17424R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-Histone H1.X/FITC Conjugated抗体

产品编号 YB-17424R-FITC
英文名称 Anti-Histone H1.X/FITC
中文名称 FITC标记的组蛋白H1家族X抗体
别    名 H1 histone family member X; Histone H1fx; H1FX; H1X_HUMAN; H1X; Histone H1x; MGC15959; MGC8350.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  表观遗传学  泛素  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Histone H1.X
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H1 family. [provided by RefSeq, Jul 2008]

Function:
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.

Subcellular Location:
NuclearC. hromosome. 

Tissue Specificity:
Expressed ubiquitously. 

Post-translational modifications:
Citrullination at Arg-62 (H1R54ci) by PADI4 takes place within the DNA-binding site of H1 and results in its displacement from chromatin and global chromatin decondensation, thereby promoting pluripotency and stem cell maintenance (By similarity).

Similarity:
Belongs to the histone H1/H5 family.
Contains 1 H15 (linker histone H1/H5 globular) domain. 

Database links:

Entrez Gene: 8971 Human

Entrez Gene: 243529 Mouse

Omim: 602785 Human

SwissProt: Q92522 Human

SwissProt: Q80ZM5 Mouse

Unigene: 33796 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications