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Anti-Histone H1.X/FITC Conjugated抗体
产品名称: Anti-Histone H1.X/FITC Conjugated抗体
英文名称: Anti-Histone H1.X/FITC
产品编号: YB--17424R-FITC
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
上海钰博生物科技有限公司
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Anti-Histone H1.X/FITC Conjugated抗体
产品编号 | YB-17424R-FITC |
英文名称 | Anti-Histone H1.X/FITC |
中文名称 | FITC标记的组蛋白H1家族X抗体 |
别 名 | H1 histone family member X; Histone H1fx; H1FX; H1X_HUMAN; H1X; Histone H1x; MGC15959; MGC8350. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 表观遗传学 泛素 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 22kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Histone H1.X |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H1 family. [provided by RefSeq, Jul 2008] Function: Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. Subcellular Location: NuclearC. hromosome. Tissue Specificity: Expressed ubiquitously. Post-translational modifications: Citrullination at Arg-62 (H1R54ci) by PADI4 takes place within the DNA-binding site of H1 and results in its displacement from chromatin and global chromatin decondensation, thereby promoting pluripotency and stem cell maintenance (By similarity). Similarity: Belongs to the histone H1/H5 family. Contains 1 H15 (linker histone H1/H5 globular) domain. Database links: Entrez Gene: 8971 Human Entrez Gene: 243529 Mouse Omim: 602785 Human SwissProt: Q92522 Human SwissProt: Q80ZM5 Mouse Unigene: 33796 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |