PTP4A3 (C-term) Peptide
产品名称： PTP4A3 (C-term) Peptide
英文名称： PTP4A3 (C-term) Peptide
产品编号： P3272
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PTP4A3.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PTP4A3.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Phosphatase of regenerating liver-3 promotes motility and metastasis of mouse melanoma cells.
Wu X, Zeng H, Zhang X, Zhao Y, Sha H, Ge X, Zhang M, Gao X, Xu Q.Am J Pathol. 2004 Jun;164(6):2039-54.
- 2.
- Structural insights into molecular function of the metastasis-associated phosphatase PRL-3.
Kozlov G, Cheng J, Ziomek E, Banville D, Gehring K, Ekiel I.J Biol Chem. 2004 Mar 19;279(12):11882-9. Epub 2004 Jan 1.
- 3.
- PRL-3 expression in metastatic cancers.
Bardelli A, Saha S, Sager JA, Romans KE, Xin B, Markowitz SD, Lengauer C, Velculescu VE, Kinzler KW, Vogelstein B.Clin Cancer Res. 2003 Nov 15;9(15):5607-15.
- Entrez GeneID:
- 11156
- Protein Accession#:
- NP_116000;O75365
- Gene Name:
- PTP4A3
- Gene Alias:
- PRL-3,PRL-R,PRL3
- Gene Description:
- protein tyrosine phosphatase type IVA, member 3
- Omim ID:
- 606449
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist. [provided by RefSeq
- Other Designations:
- potentially prenylated protein tyrosine phosphatase