KDR (phospho Y996) polyclonal antibody-抗体-抗体-生物在线
亚诺法生技股份有限公司（Abnova)
KDR (phospho Y996) polyclonal antibody

KDR (phospho Y996) polyclonal antibody

商家询价

产品名称： KDR (phospho Y996) polyclonal antibody

英文名称： KDR (phospho Y996) polyclonal antibody

产品编号： PAB0505

产品价格： null

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围：

亚诺法生技股份有限公司（Abnova)
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进入展台

  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of KDR.
  • Immunogen:
  • Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y996 of human KDR.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Recommend Usage:
  • ELISA (1:1000)
    Western Blot (1:100-500)
    Immunohistochemistry (1:50-100)
    The optimal working dilution should be determined by the end user.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • KDR (phospho Y996) polyclonal antibody (Cat # PAB0505) is used in Western blot to detect Phospho-KDR-Y996 in HMVEC cell lysate. Endothelial cells were stimulated with 50 ug/mL VEGF for 5min; 20 ug lysate from HMVEC was loaded onto an 8% gel; for Western blot, membranes were incubated O/N with KDR (phospho Y996) polyclonal antibody (Cat # PAB0505) diluted to 1 : 500 in 1% Milk/TBST. Data and Protocol kindly provided by Dr. Weis from Cheresh Lab, UCSD.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with KDR (phospho Y996) polyclonal antibody (Cat # PAB0505) which was peroxidase-conjugated to the secondary antibody followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3791
  • Protein Accession#:
  • NP_002244;P35968
  • Gene Name:
  • KDR
  • Gene Alias:
  • CD309,FLK1,VEGFR,VEGFR2
  • Gene Description:
  • kinase insert domain receptor (a type III receptor tyrosine kinase)
  • Gene Summary:
  • Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq
  • Other Designations:
  • soluble VEGFR2,vascular endothelial growth factor receptor 2

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